Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function.
Peterson BG, Hwang J, Russ JE, Schroeder JW, Freddolino PL, Baldridge RD
Cell Reports, 2023, 42 (11), 113451
View on PubMed »Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function.
Peterson BG, Hwang J, Russ JE, Schroeder JW, Freddolino PL, Baldridge RD
Cell Reports, 2023, 42 (11), 113451
View on PubMed »Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD
Moochickal Assainar B, Ragunathan K, Baldridge RD
BioRxiv : the Preprint Server for Biology, 2023
View on PubMed »Identification of ERAD-dependent degrons for the endoplasmic reticulum lumenĀ
Sharninghausen R, Hwang J, Dennison D, Baldridge RD
BioRxiv : the Preprint Server for Biology, 2023
View on PubMed »The ERAD system is restricted by elevated ceramides.
Hwang J, Peterson BG, Knupp J, Baldridge RD
Science Advances, 2023, 9 (2), eadd8579
View on PubMed »Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1.
Peterson BG, Glaser ML, Rapoport TA, Baldridge RD
eLife, 2019, 8
View on PubMed »Autoubiquitination of the Hrd1 ligase triggers protein retrotranslocation in ERAD.
Baldridge RD, Rapoport TA
Cell, 2016, 166 (2), 394-407
View on PubMed »Congratulations to Dr. Brian Peterson! The first PhD from the lab!
Congratulations on this elegant reconstitution – in collaboration with her joint mentor Kaushik Ragunathan (@Brandeis University) https://www.biorxiv.org/content/10.1101/2023.06.20.545802v1
This is an exciting discovery reporting on the first ER-localized degrons. (https://www.biorxiv.org/content/10.1101/2023.06.21.546000v1)
This is an amazing body of work congratulations! https://www.biorxiv.org/content/10.1101/2023.04.03.535444v1
Evan earned his MSc in Biological Chemistry.
Jenn Russ was selected for the GTP (a highly competitive Genetics Training Program T32 training grant)!
Jeremy Dortch was selected for the PSTP (a highly competitive Pharmacological Sciences Training Program T32 training grant)!
An important honor for amazing students.