Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1.
Peterson BG, Glaser ML, Rapoport TA, Baldridge RD
ELife, 2019, 8
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Brian Peterson, BSc (x2)
Graduate Student
Location: 3200 MSRB3
Lab Phone: (734) 936-3440
Email: bgpete@umich.edu
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Brian graduated with a dual degree in Biochemistry and Chemistry from South Dakota State University, his home state’s land grant, in May 2017. His undergraduate work focused on developing and executing a screening assay for inhibitors of multidrug resistance-associated protein 1 (MRP1) in Dr. Surtaj Iram’s lab. Brian started his graduate study through PIBS at University of Michigan in July 2017. Brian joined Baldridge’s lab and the Department of Biological Chemistry in April 2018. Brian’s current project in the lab is total mutational analysis of HRD1 to determine critical residues in substrate recognition and the retrotranslocation process.
Awards and Honors
- Protein Folding Diseases Initiative - Best Student Poster - University of Michigan (2019)
- Graduate Research Fellowship - National Science Foundation (2019)
- Halvor and Mary Christensen Award - University of Michigan (2019)
- Genetics Training Program - University of Michigan (2018)
- Mass Fellowship - University of Michigan (2017)
- Schultz-Werth Award - South Dakota State University (2017)
- Joseph F. Nelson Mentorship - South Dakota State University (2016)
- BioSNTR Fellowship - SD EPSCoR (2015)
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Publications
High-content screening of clinically tested anticancer drugs identifies novel inhibitors of human MRP1 (ABCC1).
Peterson BG, Tan KW, Osa-Andrews B, Iram SH
Pharmacological Research, 2017, 119, 313-326
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